• N fowleri enters the host through the nasal cavity

  2021-01-27

  

  N. fowleri enters the host through the nasal cavity and travels via the olfactory nerve into the Adox australia where it causes PAM (Visvesvara and Stehr-Green, 1990). The ameba most commonly infects healthy young adults and children and is able to evade the immune system but also elicits extensive

• br Materials and Methods br

  2021-01-27

  

  Materials and Methods Results Discussion Even though T cell checkpoint inhibitors alone have achieved impressive clinical benefit in some cancers, their application as single agents has had limited efficacy (Hamid et al., 2013; Wolchok et al., 2013). The resistance to immunotherapy is in pa

• PBIT mg br Acknowledgements We thank Jeffrey D Konowalchuk a

  2021-01-27

  

  Acknowledgements We thank Jeffrey D. Konowalchuk and John Sony Robbins for their technical assistance. This work was supported by Natural Sciences and Engineering Research Council of Canada (NSERC) grants to DRB (RGPIN-2013-355303) and MB (RGPIN-2014-96395). AMR was supported by NSERC Vanier Doct

• The associations between genetic factors

  2021-01-27

  

  The associations between genetic factors and socio-emotional functioning are complex and almost certainly not direct. They are mediated through a variety of developmental processes including individual differences in personality traits (Davis and Loxton, 2013, Saphire-Bernstein et al., 2011). For th

• MAPK Inhibitor Library synthesis Natural progestogens play a

  2021-01-27

  

  Natural progestogens play an important role in the stimulation of oocyte growth and maturation as well as in spermatogenesis and sperm maturation, and they act as sex pheromones in teleost fish (Kime, 1990, Kobayashi et al., 2002, Nagahama and Yamashita, 2008, Scott et al., 2010). A complex series o

• In this study we also conducted an

  2021-01-27

  

  In this study, we also conducted an analysis comparing the expression profiling of Hh genes among the sarcomas investigated. In these tumors, the IHH gene showed a higher expression level than PTCH1 gene in RMS and SS samples (pDovitinib Lactate in human RMS cell lines as well as mouse NIH-3T3 fibr

• br Materials and methods br Results br

  2021-01-27

  

  Materials and methods Results Discussion Our previous study showed that ERRγ negatively regulates osteoblast differentiation via inhibiting Runx2 transactivity (Jeong et al., 2009). In the present study, we found that ERRγ also induced miR-433 in osteogenic mesenchymal cell lineage C3H10T1/

• NF B is a family of

  2021-01-26

  

  NF-κB is a family of protein mediators that regulate various innate and adaptive immune responses [29,30]. The NF-κB family consists of the following five proteins: c-Rel (Rel); p65 (RelA); RelB; p50(NF-κB1); and p52(NF-κB2). It has been confirmed that NF-κB is activated by TNF family cytokines, suc

• trp channel In the present study we first examined the

  2021-01-26

  

  In the present study, we first examined the in vivo and ex vivo effects of androgens on ep1 trp channel in the olfactory rosette of male B. sinensis. Thereafter, we cloned two different B.sinensis ar cDNAs and investigated their roles in the effects of 11-KT on ep1 expression. Material and metho

• sodium butyrate Several studies on the collagen

  2021-01-26

  

  Several studies on the collagen receptor DDR1 have revealed a defined collagen signaling pathway that causes cell scattering and cadherin switching. As mentioned earlier, DDR sodium butyrate on collagens are distinct from integrin binding sites; therefore, the same collagen protein can bind to DDR a

• The primary aim of this study was

  2021-01-26

  

  The primary aim of this study was to evaluate DAPK methylation as a tumor marker which is not only detected in the primary tumor but also in the serum of patients. We used matched pre-operative serum samples to determine the correlation of tumor and serum results. Despite an equal methylation freque

• Currently it is not known if drought induces changes

  2021-01-26

  

  Currently, it is not known if drought induces changes in the cysteine protease Peramivir of soybean nodules. The available annotation of the soybean genome, in Phytozome (www.phytozome.net) has identified 706 C1 cysteine protease sequences and 75 C13 cysteine proteases. We have previously reported

• It is well known that CysLTs

  2021-01-26

  

  It is well known that CysLTs exert potent contractile action on human bronchial smooth muscles through activation of CysLT1 receptors. Indeed, in vitro antigen-induced contraction of passively sensitized human bronchial tissue is markedly suppressed by a pre-treatment with CysLT1 receptor antagonist

• br Results br Discussion Drug resistance

  2021-01-26

  

  Results Discussion Drug resistance poses the greatest hurdle of achieving high efficacy with AADs in cancer patients. AAD-treated cancer patients often encounter intrinsic and evasive drug resistance that diminishes the therapeutic efficacy to only minor survival benefits in most cancer types.

• A variety of epidemiological and clinical studies suggest th

  2021-01-26

  

  A variety of epidemiological and clinical studies suggest that light alcohol consumption may exert a favorable effects on BP levels but chronic heavy alcohol consumtion causes sustained BP elevation [16], [17]. The hypertensive effect of heavy drinking occurs with all forms of alcohol (i.e. beer win

11003 records 408/734 page Previous Next First page 上5页 406407408409410 下5页 Last page